Designed alpha-helical barrels for charge-selective peptide translocation

Synthetic alpha-helix based pores for selective sensing of peptides have not been characterized previously. Here, we report large transmembrane pores, pPorA formed from short synthetic alpha-helical peptides of tunable conductance and selectivity for single-molecule sensing of peptides. We quantifie...

Descripción completa

Detalles Bibliográficos
Autores principales: R., Smrithi Krishnan, Puthumadathil, Neethu, Shaji, Amina H., Santhosh Kumar, K., Mohan, Gayathri, Mahendran, Kozhinjampara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178987/
https://www.ncbi.nlm.nih.gov/pubmed/34163795
http://dx.doi.org/10.1039/d0sc04856a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178987/
https://www.ncbi.nlm.nih.gov/pubmed/34163795
http://dx.doi.org/10.1039/d0sc04856a

Ejemplares similares