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Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)

BACKGROUND: Perinatal hypoxia and subsequent reduction of cerebral blood flow leads to neonatal hypoxic-ischemic brain injury (HIBI), resulting in severe disability and even death. Preconditioning or post-conditioning with sevoflurane protects against cerebral injury. This study investigated the mec...

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Detalles Bibliográficos
Autores principales: Wang, HuaiMing, Xu, YiQuan, Zhu, Shuying, Li, XueMing, Zhang, HongWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8178995/
https://www.ncbi.nlm.nih.gov/pubmed/34059615
http://dx.doi.org/10.12659/MSM.930042