Asymmetric construction of pyrido[1,2-a]-1H-indole derivatives via a gold-catalyzed cycloisomerization

Pyrido[1,2-a]-1H-indoles are important scaffolds found in many biologically active compounds. Herein, we first developed an IPrAuCl/AgSbF(6)-catalyzed cycloisomerization of N-1,3-disubstituted allenyl indoles affording pyrido[1,2-a]-1H-indoles. Then the axial-to-central chirality transfer starting f...

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Detalles Bibliográficos
Autores principales: Jiang, Feng, Fu, Chunling, Ma, Shengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179015/
https://www.ncbi.nlm.nih.gov/pubmed/34163802
http://dx.doi.org/10.1039/d0sc05619g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179015/
https://www.ncbi.nlm.nih.gov/pubmed/34163802
http://dx.doi.org/10.1039/d0sc05619g

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