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Investigation on the reactivity of nucleophilic radiohalogens with arylboronic acids in water: access to an efficient single-step method for the radioiodination and astatination of antibodies

Easy access to radioiodinated and (211)At-labelled bio(macro)molecules is essential to develop new strategies in nuclear imaging and targeted radionuclide therapy of cancers. Yet, the labelling of complex molecules with heavy radiohalogens is often poorly effective due to the multiple steps and inte...

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Detalles Bibliográficos
Autores principales: Berdal, Marion, Gouard, Sébastien, Eychenne, Romain, Marionneau-Lambot, Séverine, Croyal, Mikaël, Faivre-Chauvet, Alain, Chérel, Michel, Gaschet, Joëlle, Gestin, Jean-François, Guérard, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179031/
https://www.ncbi.nlm.nih.gov/pubmed/34163909
http://dx.doi.org/10.1039/d0sc05191h