Cu-catalyzed hydroxycyclopropanol ring-opening cyclization to tetrahydrofurans and tetrahydropyrans: short total syntheses of hyperiones

Tetrahydrofurans (THFs) and tetrahydropyrans (THPs) are important core scaffolds frequently found in many molecules of medicinal importance. Herein, we report a novel copper-catalyzed hydroxycyclopropanol ring-opening cyclization methodology to synthesize di- or tri-substituted THFs and THPs. In thi...

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Detalles Bibliográficos
Autores principales: Liang, Weida, Cai, Xinpei, Dai, Mingji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179039/
https://www.ncbi.nlm.nih.gov/pubmed/34163894
http://dx.doi.org/10.1039/d0sc05556e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179039/
https://www.ncbi.nlm.nih.gov/pubmed/34163894
http://dx.doi.org/10.1039/d0sc05556e

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