Ritter-enabled catalytic asymmetric chloroamidation of olefins

Intermolecular asymmetric haloamination reactions are challenging due to the inherently high halenium affinity (HalA) of the nitrogen atom, which often leads to N-halogenated products as a kinetic trap. To circumvent this issue, acetonitrile, possessing a low HalA, was used as the nucleophile in the...

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Detalles Bibliográficos
Autores principales: Steigerwald, Daniel C., Soltanzadeh, Bardia, Sarkar, Aritra, Morgenstern, Cecilia C., Staples, Richard J., Borhan, Babak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179065/
https://www.ncbi.nlm.nih.gov/pubmed/34163947
http://dx.doi.org/10.1039/d0sc05224h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179065/
https://www.ncbi.nlm.nih.gov/pubmed/34163947
http://dx.doi.org/10.1039/d0sc05224h

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