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A pyrone remodeling strategy to access diverse heterocycles: application to the synthesis of fascaplysin natural products

The synthesis of diverse N-fused heterocycles, including the pyrido[1,2-a]indole scaffold, using an efficient pyrone remodeling strategy is described. The pyrido[1,2-a]indole core was demonstrated to be a versatile scaffold that can be site-selectively functionalized. The utility of this novel annul...

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Detalles Bibliográficos
Autores principales: Palani, Vignesh, Perea, Melecio A., Gardner, Kristen E., Sarpong, Richmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179101/
https://www.ncbi.nlm.nih.gov/pubmed/34163915
http://dx.doi.org/10.1039/d0sc06317g