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Intermediates involved in serotonin oxidation catalyzed by Cu bound Aβ peptides
The degradation of neurotransmitters is a hallmark feature of Alzheimer's disease (AD). Copper bound Aβ peptides, invoked to be involved in the pathology of AD, are found to catalyze the oxidation of serotonin (5-HT) by H(2)O(2). A combination of EPR and resonance Raman spectroscopy reveals the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179298/ https://www.ncbi.nlm.nih.gov/pubmed/34163956 http://dx.doi.org/10.1039/d0sc06258h |