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Intermediates involved in serotonin oxidation catalyzed by Cu bound Aβ peptides

The degradation of neurotransmitters is a hallmark feature of Alzheimer's disease (AD). Copper bound Aβ peptides, invoked to be involved in the pathology of AD, are found to catalyze the oxidation of serotonin (5-HT) by H(2)O(2). A combination of EPR and resonance Raman spectroscopy reveals the...

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Detalles Bibliográficos
Autores principales: Nath, Arnab Kumar, Ghatak, Arnab, Dey, Abhishek, Dey, Somdatta Ghosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179298/
https://www.ncbi.nlm.nih.gov/pubmed/34163956
http://dx.doi.org/10.1039/d0sc06258h

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