Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-β

Pathophysiological shifts in the cerebral levels of sphingolipids in Alzheimer's disease (AD) patients suggest a link between sphingolipid metabolism and the disease pathology. Sphingosine (SP), a structural backbone of sphingolipids, is an amphiphilic molecule that is able to undergo aggregati...

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Detalles Bibliográficos
Autores principales: Yi, Yelim, Lin, Yuxi, Han, Jiyeon, Lee, Hyuck Jin, Park, Nahye, Nam, Geewoo, Park, Young S., Lee, Young-Ho, Lim, Mi Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179336/
https://www.ncbi.nlm.nih.gov/pubmed/34164011
http://dx.doi.org/10.1039/d0sc04366d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179336/
https://www.ncbi.nlm.nih.gov/pubmed/34164011
http://dx.doi.org/10.1039/d0sc04366d

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