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Palladium catalyzed synthesis of indolizines via the carbonylative coupling of bromopyridines, imines and alkynes
We report herein the development of a palladium-catalyzed, multicomponent synthesis of indolizines. The reaction proceeds via the carbonylative formation of a high energy, mesoionic pyridine-based 1,3-dipole, which can undergo spontaneous cycloaddition with alkynes. Overall, this provides a route to...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179343/ https://www.ncbi.nlm.nih.gov/pubmed/34163991 http://dx.doi.org/10.1039/d0sc03977b |