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Fluorogenic probes for detecting deacylase and demethylase activity towards post-translationally-modified lysine residues

Reversible enzymatic post-translational modification of the ε-amino groups of lysine residues (e.g. N-acylation reactions) plays an important role in regulating the cellular activities of numerous proteins. This study describes how enzyme catalyzed N-deprotection of lysine residues of non-fluorescen...

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Detalles Bibliográficos
Autores principales: Hori, Yuichiro, Nishiura, Miyako, Tao, Tomomi, Baba, Reisuke, Bull, Steven D., Kikuchi, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179349/
https://www.ncbi.nlm.nih.gov/pubmed/34164016
http://dx.doi.org/10.1039/d0sc06551j