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Trifluoromethanesulfonyl azide as a bifunctional reagent for metal-free azidotrifluoromethylation of unactivated alkenes

Vicinal trifluoromethyl azides have widespread applications in organic synthesis and drug development. However, their preparation is generally limited to transition-metal-catalyzed three-component reactions. We report here a simple and metal-free method that rapidly provides these building blocks fr...

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Detalles Bibliográficos
Autores principales: Huang, Hong-Gui, Li, Weishuang, Zhong, Dayou, Wang, Hu-Chong, Zhao, Jing, Liu, Wen-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179360/
https://www.ncbi.nlm.nih.gov/pubmed/34164089
http://dx.doi.org/10.1039/d0sc06473d