Directed evolution of cyclic peptides for inhibition of autophagy

In recent decades it has become increasingly clear that induction of autophagy plays an important role in the development of treatment resistance and dormancy in many cancer types. Unfortunately, chloroquine (CQ) and hydroxychloroquine (HCQ), two autophagy inhibitors in clinical trials, suffer from...

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Detalles Bibliográficos
Autores principales: Gray, Joshua P., Uddin, Md. Nasir, Chaudhari, Rajan, Sutton, Margie N., Yang, Hailing, Rask, Philip, Locke, Hannah, Engel, Brian J., Batistatou, Nefeli, Wang, Jing, Grindel, Brian J., Bhattacharya, Pratip, Gammon, Seth T., Zhang, Shuxing, Piwnica-Worms, David, Kritzer, Joshua A., Lu, Zhen, Bast, Robert C., Millward, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179393/
https://www.ncbi.nlm.nih.gov/pubmed/34163626
http://dx.doi.org/10.1039/d0sc03603j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179393/
https://www.ncbi.nlm.nih.gov/pubmed/34163626
http://dx.doi.org/10.1039/d0sc03603j

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