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Sequestration within biomolecular condensates inhibits Aβ-42 amyloid formation

Biomolecular condensates are emerging as an efficient strategy developed by cells to control biochemical reactions in space and time by locally modifying composition and environment. Yet, local increase in protein concentration within these compartments could promote aberrant aggregation events, inc...

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Detalles Bibliográficos
Autores principales: Küffner, Andreas M., Linsenmeier, Miriam, Grigolato, Fulvio, Prodan, Marc, Zuccarini, Remo, Capasso Palmiero, Umberto, Faltova, Lenka, Arosio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179469/
https://www.ncbi.nlm.nih.gov/pubmed/34163700
http://dx.doi.org/10.1039/d0sc04395h