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Fluorescent probe for the imaging of superoxide and peroxynitrite during drug-induced liver injury

Drug-induced liver injury (DILI) is an important cause of potentially fatal liver disease. Herein, we report the development of a molecular probe (LW-OTf) for the detection and imaging of two biomarkers involved in DILI. Initially, primary reactive oxygen species (ROS) superoxide (O(2)˙(−)) selectiv...

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Detalles Bibliográficos
Autores principales: Wu, Luling, Liu, Jihong, Tian, Xue, Groleau, Robin R., Bull, Steven D., Li, Ping, Tang, Bo, James, Tony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179478/
https://www.ncbi.nlm.nih.gov/pubmed/34163661
http://dx.doi.org/10.1039/d0sc05937d