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Covalent cell surface recruitment of chemotherapeutic polymers enhances selectivity and activity
Synthetic macromolecular chemotherapeutics inspired by host defence peptides can disrupt cell membranes and are emerging as agents for the treatment of cancer and infections. However, their off-target effects remain a major unmet challenge. Here we introduce a covalent recruitment strategy, whereby...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179505/ https://www.ncbi.nlm.nih.gov/pubmed/34163721 http://dx.doi.org/10.1039/d0sc06580c |