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Rapid synthesis of pomalidomide-conjugates for the development of protein degrader libraries
Current methods for the preparation of heterobifunctional pomalidomide-conjugates rely on methods that are often low yielding and produce intractable byproducts. Herein we describe our strategy for the reliable and succinct preparation of pomalidomide-linkers which is essential to the formation of t...
Autores principales: | Brownsey, Duncan K., Rowley, Ben C., Gorobets, Evgueni, Gelfand, Benjamin S., Derksen, Darren J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179520/ https://www.ncbi.nlm.nih.gov/pubmed/34163717 http://dx.doi.org/10.1039/d0sc05442a |
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