A single point mutation converts a proton-pumping rhodopsin into a red-shifted, turn-on fluorescent sensor for chloride

The visualization of chloride in living cells with fluorescent sensors is linked to our ability to design hosts that can overcome the energetic penalty of desolvation to bind chloride in water. Fluorescent proteins can be used as biological supramolecular hosts to address this fundamental challenge....

Descripción completa

Detalles Bibliográficos
Autores principales: Tutol, Jasmine N., Lee, Jessica, Chi, Hsichuan, Faizuddin, Farah N., Abeyrathna, Sameera S., Zhou, Qin, Morcos, Faruck, Meloni, Gabriele, Dodani, Sheel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179538/
https://www.ncbi.nlm.nih.gov/pubmed/34163777
http://dx.doi.org/10.1039/d0sc06061e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179538/
https://www.ncbi.nlm.nih.gov/pubmed/34163777
http://dx.doi.org/10.1039/d0sc06061e

Ejemplares similares