A highly selective decarboxylative deuteration of carboxylic acids

In this paper, we report a mild and practical method for precise deuteration of aliphatic carboxylic acids by synergistic photoredox and HAT catalysis. The reaction delivers excellent D-incorporation (up to 99%) at predicted sites even in substrates bearing reactive C–H bonds or versatile functional...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Nian, Ning, Yunyun, Wu, Xiaopeng, Xie, Jin, Li, Weipeng, Zhu, Chengjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179560/
https://www.ncbi.nlm.nih.gov/pubmed/34163771
http://dx.doi.org/10.1039/d1sc00528f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179560/
https://www.ncbi.nlm.nih.gov/pubmed/34163771
http://dx.doi.org/10.1039/d1sc00528f

Ejemplares similares