5-Hydroxy-pyrrolone based building blocks as maleimide alternatives for protein bioconjugation and single-site multi-functionalization

Recent dramatic expansion in potential uses of protein conjugates has fueled the development of a wide range of protein modification methods; however, the desirable single-site multi-functionalization of proteins has remained a particularly intransigent challenge. Herein, we present the application...

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Detalles Bibliográficos
Autores principales: De Geyter, Ewout, Antonatou, Eirini, Kalaitzakis, Dimitris, Smolen, Sabina, Iyer, Abhishek, Tack, Laure, Ongenae, Emiel, Vassilikogiannakis, Georgios, Madder, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179572/
https://www.ncbi.nlm.nih.gov/pubmed/34163760
http://dx.doi.org/10.1039/d0sc05881e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179572/
https://www.ncbi.nlm.nih.gov/pubmed/34163760
http://dx.doi.org/10.1039/d0sc05881e

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