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Surmounting tumor resistance to metallodrugs by co-loading a metal complex and siRNA in nanoparticles

Copper complexes are promising anticancer agents widely studied to overcome tumor resistance to metal-based anticancer drugs. Nevertheless, copper complexes per se encounter drug resistance from time to time. Adenosine-5′-triphosphate (ATP)-responsive nanoparticles containing a copper complex CTND a...

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Detalles Bibliográficos
Autores principales: Qiao, Hongzhi, Zhang, Lei, Fang, Dong, Zhu, Zhenzhu, He, Weijiang, Hu, Lihong, Di, Liuqing, Guo, Zijian, Wang, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179575/
https://www.ncbi.nlm.nih.gov/pubmed/34163720
http://dx.doi.org/10.1039/d0sc06680j