Cleavable and tunable cysteine-specific arylation modification with aryl thioethers

Cysteine represents an attractive target for peptide/protein modification due to the intrinsic high nucleophilicity of the thiol group and low natural abundance. Herein, a cleavable and tunable covalent modification approach for cysteine containing peptides/proteins with our newly designed aryl thio...

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Detalles Bibliográficos
Autores principales: Li, Jian, Deng, Jun-Jie, Yin, Zhibin, Hu, Qi-Long, Ge, Yang, Song, Zhendong, Zhang, Ying, Chan, Albert S. C., Li, Huilin, Xiong, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179606/
https://www.ncbi.nlm.nih.gov/pubmed/34168774
http://dx.doi.org/10.1039/d0sc06576e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179606/
https://www.ncbi.nlm.nih.gov/pubmed/34168774
http://dx.doi.org/10.1039/d0sc06576e

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