Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation in solution and on DNA

A highly efficient and versatile method for construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation of alkyl and aryl thiols with aryl iodides under mild conditions is developed. The method exhibits a broad substrate scope for thiols, aryl iodides and amino acid units....

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Detalles Bibliográficos
Autores principales: Yang, Peng, Wang, Xuan, Li, Bo, Yang, Yixuan, Yue, Jinfeng, Suo, Yanrui, Tong, Huarong, He, Gang, Lu, Xiaojie, Chen, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179660/
https://www.ncbi.nlm.nih.gov/pubmed/34168804
http://dx.doi.org/10.1039/d1sc00789k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179660/
https://www.ncbi.nlm.nih.gov/pubmed/34168804
http://dx.doi.org/10.1039/d1sc00789k

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