Cargando…
Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation in solution and on DNA
A highly efficient and versatile method for construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation of alkyl and aryl thiols with aryl iodides under mild conditions is developed. The method exhibits a broad substrate scope for thiols, aryl iodides and amino acid units....
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179660/ https://www.ncbi.nlm.nih.gov/pubmed/34168804 http://dx.doi.org/10.1039/d1sc00789k |