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The Functional Hallmarks of Cancer Predisposition Genes

The canonical model for hereditary cancer predisposition is a cancer predisposition gene (CPG) that drives either one or both of two fundamental hallmarks of cancer, defective genomic integrity and deregulated cell proliferation, ultimately resulting in the accumulation of mutations within cells. Th...

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Detalles Bibliográficos
Autores principales: Capellini, Alexandra, Williams, Matthew, Onel, Kenan, Huang, Kuan-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179747/
https://www.ncbi.nlm.nih.gov/pubmed/34103990
http://dx.doi.org/10.2147/CMAR.S311548