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The Functional Hallmarks of Cancer Predisposition Genes
The canonical model for hereditary cancer predisposition is a cancer predisposition gene (CPG) that drives either one or both of two fundamental hallmarks of cancer, defective genomic integrity and deregulated cell proliferation, ultimately resulting in the accumulation of mutations within cells. Th...
Autores principales: | Capellini, Alexandra, Williams, Matthew, Onel, Kenan, Huang, Kuan-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179747/ https://www.ncbi.nlm.nih.gov/pubmed/34103990 http://dx.doi.org/10.2147/CMAR.S311548 |
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