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Inhibition of the Axl pathway impairs breast and prostate cancer metastasis to the bones and bone remodeling

Approximately 90% of cancer-related deaths result from cancer metastasis. In prostate and breast cancers, bone is the most common site of cancer cell dissemination. Key steps in the metastatic cascade are promoted through upregulation of critical cell signaling pathways in neoplastic cells. The pres...

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Detalles Bibliográficos
Autores principales: Tanaka, Mai, Dykes, Samantha S., Siemann, Dietmar W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179919/
https://www.ncbi.nlm.nih.gov/pubmed/33791875
http://dx.doi.org/10.1007/s10585-021-10093-z