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Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression

Genetic studies in ASD have mostly focused on the proband, with no clear understanding of parental genetic contributions to fetal neurodevelopment. Among parental etiological factors, perinatal maternal inflammation secondary to autoimmunity, infections, and toxins is associated with ASD. However, t...

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Detalles Bibliográficos
Autores principales: Jaini, Ritika, Wolf, Matthew R., Yu, Qi, King, Alexander T., Frazier, Thomas W., Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179926/
https://www.ncbi.nlm.nih.gov/pubmed/34091589
http://dx.doi.org/10.1038/s41398-021-01472-x