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Metabolic protein phosphoglycerate kinase 1 confers lung cancer migration by directly binding HIV Tat specific factor 1

Phosphoglycerate kinase (PGK) is involved in glycolytic and various metabolic events. Dysfunction of PGK may induce metabolic reprogramming and the Warburg effect. In this study, we demonstrated that PGK1, but not PGK2, may play a key role in tumorigenesis and is associated with metastasis. We obser...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Chan, Chan, Ming-Hsien, Li, Chien-Hsiu, Yang, Chih-Jen, Tseng, Yu-Wen, Tsai, Hsing-Fang, Chiou, Jean, Hsiao, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179927/
https://www.ncbi.nlm.nih.gov/pubmed/34091600
http://dx.doi.org/10.1038/s41420-021-00520-1