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Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages

A chronic low-grade inflammation within adipose tissue (AT) seems to be the link between obesity and some of its associated diseases. One hallmark of this AT inflammation is the accumulation of AT macrophages (ATMs) around dead or dying adipocytes, forming so-called crown-like structures (CLS). To i...

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Detalles Bibliográficos
Autores principales: Lindhorst, Andreas, Raulien, Nora, Wieghofer, Peter, Eilers, Jens, Rossi, Fabio M. V., Bechmann, Ingo, Gericke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179930/
https://www.ncbi.nlm.nih.gov/pubmed/34091595
http://dx.doi.org/10.1038/s41419-021-03872-9