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Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages
A chronic low-grade inflammation within adipose tissue (AT) seems to be the link between obesity and some of its associated diseases. One hallmark of this AT inflammation is the accumulation of AT macrophages (ATMs) around dead or dying adipocytes, forming so-called crown-like structures (CLS). To i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179930/ https://www.ncbi.nlm.nih.gov/pubmed/34091595 http://dx.doi.org/10.1038/s41419-021-03872-9 |