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Neuroprotection by Wld(S) depends on retinal ganglion cell type and age in glaucoma

BACKGROUND: Early challenges to axonal physiology, active transport, and ultrastructure are endemic to age-related neurodegenerative disorders, including those affecting the optic nerve. Chief among these, glaucoma causes irreversible vision loss through sensitivity to intraocular pressure (IOP) tha...

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Detalles Bibliográficos
Autores principales: Risner, Michael L., Pasini, Silvia, McGrady, Nolan R., D’Alessandro, Karis B., Yao, Vincent, Cooper, Melissa L., Calkins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180099/
https://www.ncbi.nlm.nih.gov/pubmed/34090501
http://dx.doi.org/10.1186/s13024-021-00459-y