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Neuroprotection by Wld(S) depends on retinal ganglion cell type and age in glaucoma
BACKGROUND: Early challenges to axonal physiology, active transport, and ultrastructure are endemic to age-related neurodegenerative disorders, including those affecting the optic nerve. Chief among these, glaucoma causes irreversible vision loss through sensitivity to intraocular pressure (IOP) tha...
Autores principales: | Risner, Michael L., Pasini, Silvia, McGrady, Nolan R., D’Alessandro, Karis B., Yao, Vincent, Cooper, Melissa L., Calkins, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180099/ https://www.ncbi.nlm.nih.gov/pubmed/34090501 http://dx.doi.org/10.1186/s13024-021-00459-y |
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