EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation

BACKGROUND: The echinoderm microtubule-associated protein-like-4 anaplastic lymphoma kinase (EML4-ALK) fusion gene was identified in a subset of non-small cell lung cancer (NSCLC) patients. They responded positively to ALK inhibitors. This study aimed to characterize the mechanisms triggered by EML4...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ying, Li, Yongwen, Zhang, Hongbing, Shi, Ruifeng, Zhang, Zihe, Liu, Hongyu, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180148/
https://www.ncbi.nlm.nih.gov/pubmed/34090412
http://dx.doi.org/10.1186/s12890-021-01553-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180148/
https://www.ncbi.nlm.nih.gov/pubmed/34090412
http://dx.doi.org/10.1186/s12890-021-01553-z

Ejemplares similares