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EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation

BACKGROUND: The echinoderm microtubule-associated protein-like-4 anaplastic lymphoma kinase (EML4-ALK) fusion gene was identified in a subset of non-small cell lung cancer (NSCLC) patients. They responded positively to ALK inhibitors. This study aimed to characterize the mechanisms triggered by EML4...

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Detalles Bibliográficos
Autores principales:	Li, Ying, Li, Yongwen, Zhang, Hongbing, Shi, Ruifeng, Zhang, Zihe, Liu, Hongyu, Chen, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180148/ https://www.ncbi.nlm.nih.gov/pubmed/34090412 http://dx.doi.org/10.1186/s12890-021-01553-z

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