“Don’t Phos Over Tau”: recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer’s disease and other tauopathies

Phosphorylation is one of the most prevalent post-translational modifications found in aggregated tau isolated from Alzheimer’s disease (AD) patient brains. In tauopathies like AD, increased phosphorylation or hyperphosphorylation can contribute to microtubule dysfunction and is associated with tau...

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Detalles Bibliográficos
Autores principales: Xia, Yuxing, Prokop, Stefan, Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180161/
https://www.ncbi.nlm.nih.gov/pubmed/34090488
http://dx.doi.org/10.1186/s13024-021-00460-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180161/
https://www.ncbi.nlm.nih.gov/pubmed/34090488
http://dx.doi.org/10.1186/s13024-021-00460-5

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