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CircPRDM2 Contributes to Doxorubicin Resistance of Osteosarcoma by Elevating EZH2 via Sponging miR-760

BACKGROUND: Circular RNAs (circRNAs) are implicated in the chemoresistance of human cancers. However, the functions of circRNA PR/SET domain 2 (circPRDM2) in the resistance of osteosarcoma (OS) to doxorubicin (DXR) are unknown. METHODS: Quantitative real-time polymerase chain reaction (qRT-PCR) assa...

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Detalles Bibliográficos
Autores principales: Yuan, Jianjun, Liu, Yan, Zhang, Quan, Ren, Zhishuai, Li, Guang, Tian, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180268/
https://www.ncbi.nlm.nih.gov/pubmed/34103997
http://dx.doi.org/10.2147/CMAR.S295147