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Using CRISPRa and CRISPRi Technologies to Study the Biological Functions of ITGB5, TIMP1, and TMEM176B in Prostate Cancer Cells

Although ITGB5, TIMP1, and TMEM176B are abnormally expressed in several cancers, their molecular biological mechanisms in prostate cancer cells are still to be investigated. The gene regulation technogies based on CRISPR transcription factors could be used to investigate the biological functions of...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Feng, Qingxing, Hu, Kun, Cheng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180862/
https://www.ncbi.nlm.nih.gov/pubmed/34109215
http://dx.doi.org/10.3389/fmolb.2021.676021