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Sirtuin 2 (SIRT2): Confusing Roles in the Pathophysiology of Neurological Disorders

As a type of nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylases, sirtuin 2 (SIRT2) is predominantly found in the cytoplasm of cells in the central nervous system (CNS), suggesting its potential role in neurological disorders. Though SIRT2 is generally acknowledged to accelerate the de...

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Detalles Bibliográficos
Autores principales: Chen, Xiuqi, Lu, Wenmei, Wu, Danhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180884/
https://www.ncbi.nlm.nih.gov/pubmed/34108853
http://dx.doi.org/10.3389/fnins.2021.614107