Attenuated SIRT1 Activity Leads to PER2 Cytoplasmic Localization and Dampens the Amplitude of Bmal1 Promoter-Driven Circadian Oscillation

The circadian clock possesses robust systems to maintain the rhythm approximately 24 h, from cellular to organismal levels, whereas aging is known to be one of the risk factors linked to the alternation of circadian physiology and behavior. The amount of many metabolites in the cells/body is altered...

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Detalles Bibliográficos
Autores principales: Ashimori, Atsushige, Nakahata, Yasukazu, Sato, Toshiya, Fukamizu, Yuichiro, Matsui, Takaaki, Yoshitane, Hikari, Fukada, Yoshitaka, Shinohara, Kazuyuki, Bessho, Yasumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180908/
https://www.ncbi.nlm.nih.gov/pubmed/34108855
http://dx.doi.org/10.3389/fnins.2021.647589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180908/
https://www.ncbi.nlm.nih.gov/pubmed/34108855
http://dx.doi.org/10.3389/fnins.2021.647589

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