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Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-κB-STAT3 axis

Previously, we found that rosmarinic acid (RA) exerted anti-inflammatory activities in a dextran sulfate sodium (DSS)-induced colitis model. Here, we investigated the anti-tumor effects of RA on colitis-associated colon cancer (CAC) and the underlying molecular mechanisms. We established an azoxymet...

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Detalles Bibliográficos
Autores principales: Jin, Bo-Ram, Chung, Kyung-Sook, Hwang, Soonjae, Hwang, Sam Noh, Rhee, Ki-Jong, Lee, Minho, An, Hyo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8180929/
https://www.ncbi.nlm.nih.gov/pubmed/34077834
http://dx.doi.org/10.1016/j.neo.2021.05.002