Intramuscular Expression of Plasmid-Encoded FVII-Fc Immunoconjugate for Tumor Immunotherapy by Targeting Tumoral Blood Vessels and Cells

Tissue factor (TF) has been confirmed to be specifically expressed by vascular endothelial cells (VECs) in solid tumors and certain types of malignant tumor cells. Coagulation factor VII (FVII) can specifically bind to TF with high affinity, so the FVII-TF interaction provides an ideal target for tu...

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Detalles Bibliográficos
Autores principales: Ma, Liping, Wang, Guanru, Liu, Sijia, Bi, Feng, Liu, Ming, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181131/
https://www.ncbi.nlm.nih.gov/pubmed/34109110
http://dx.doi.org/10.3389/fonc.2021.638591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181131/
https://www.ncbi.nlm.nih.gov/pubmed/34109110
http://dx.doi.org/10.3389/fonc.2021.638591

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