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Offspring of Obese Dams Exhibit Sex-Differences in Pancreatic Heparan Sulfate Glycosaminoglycans and Islet Insulin Secretion

Offspring of obese mothers suffer higher risks of type 2 diabetes due to increased adiposity and decreased β cell function. To date, the sex-differences in offspring islet insulin secretion during early life has not been evaluated extensively, particularly prior to weaning at postnatal day 21 (P21)....

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Detalles Bibliográficos
Autores principales: Casasnovas, Jose, Damron, Christopher Luke, Jarrell, James, Orr, Kara S., Bone, Robert N., Archer-Hartmann, Stephanie, Azadi, Parastoo, Kua, Kok Lim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181410/
https://www.ncbi.nlm.nih.gov/pubmed/34108935
http://dx.doi.org/10.3389/fendo.2021.658439