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Offspring of Obese Dams Exhibit Sex-Differences in Pancreatic Heparan Sulfate Glycosaminoglycans and Islet Insulin Secretion
Offspring of obese mothers suffer higher risks of type 2 diabetes due to increased adiposity and decreased β cell function. To date, the sex-differences in offspring islet insulin secretion during early life has not been evaluated extensively, particularly prior to weaning at postnatal day 21 (P21)....
Autores principales: | Casasnovas, Jose, Damron, Christopher Luke, Jarrell, James, Orr, Kara S., Bone, Robert N., Archer-Hartmann, Stephanie, Azadi, Parastoo, Kua, Kok Lim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181410/ https://www.ncbi.nlm.nih.gov/pubmed/34108935 http://dx.doi.org/10.3389/fendo.2021.658439 |
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