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Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

Treatment with exogenous GLP-2 has been shown to accelerate the growth of intestinal adenomas and adenocarcinomas in experimental models of colonic neoplasia, however, the role of endogenous GLP-2 in tumor promotion is less well known. Mice with a global deletion of the glucagon receptor (Gcgr(-/-))...

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Detalles Bibliográficos
Autores principales: Hunt, Jenna Elizabeth, Yassin, Mohammad, Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul, Kissow, Hannelouise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181411/
https://www.ncbi.nlm.nih.gov/pubmed/34108943
http://dx.doi.org/10.3389/fendo.2021.695145