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Integration of Immunome With Disease-Gene Network Reveals Common Cellular Mechanisms Between IMIDs and Drug Repurposing Strategies

OBJECTIVE: Development and progression of immune-mediated inflammatory diseases (IMIDs) involve intricate dysregulation of the disease-associated genes (DAGs) and their expressing immune cells. Identifying the crucial disease-associated cells (DACs) in IMIDs has been challenging due to the underlyin...

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Detalles Bibliográficos
Autores principales: Devaprasad, Abhinandan, Radstake, Timothy R. D. J., Pandit, Aridaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181425/
https://www.ncbi.nlm.nih.gov/pubmed/34108969
http://dx.doi.org/10.3389/fimmu.2021.669400