Admixed Populations Improve Power for Variant Discovery and Portability in Genome-Wide Association Studies

Genome-wide association studies (GWAS) are primarily conducted in single-ancestry settings. The low transferability of results has limited our understanding of human genetic architecture across a range of complex traits. In contrast to homogeneous populations, admixed populations provide an opportun...

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Detalles Bibliográficos
Autores principales: Lin, Meng, Park, Danny S., Zaitlen, Noah A., Henn, Brenna M., Gignoux, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181458/
https://www.ncbi.nlm.nih.gov/pubmed/34108994
http://dx.doi.org/10.3389/fgene.2021.673167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181458/
https://www.ncbi.nlm.nih.gov/pubmed/34108994
http://dx.doi.org/10.3389/fgene.2021.673167

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