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Structural Design and Analysis of the RHOA-ARHGEF1 Binding Mode: Challenges and Applications for Protein-Protein Interface Prediction

The interaction between two proteins may involve local movements, such as small side-chains re-positioning or more global allosteric movements, such as domain rearrangement. We studied how one can build a precise and detailed protein-protein interface using existing protein-protein docking methods,...

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Detalles Bibliográficos
Autores principales: Gheyouche, Ennys, Bagueneau, Matthias, Loirand, Gervaise, Offmann, Bernard, Téletchéa, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8181724/
https://www.ncbi.nlm.nih.gov/pubmed/34109211
http://dx.doi.org/10.3389/fmolb.2021.643728