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Differential Regulation of GPCRs—Are GRK Expression Levels the Key?

G protein-coupled receptors (GPCRs) comprise the largest family of transmembrane receptors and their signal transduction is tightly regulated by GPCR kinases (GRKs) and β-arrestins. In this review, we discuss novel aspects of the regulatory GRK/β-arrestin system. Therefore, we briefly revise the ori...

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Detalles Bibliográficos
Autores principales: Matthees, Edda S. F., Haider, Raphael S., Hoffmann, Carsten, Drube, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182058/
https://www.ncbi.nlm.nih.gov/pubmed/34109182
http://dx.doi.org/10.3389/fcell.2021.687489