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Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation

The ubiquitin (Ub)-proteasome system is vital to nearly every biological process in eukaryotes. Specifically, the conjugation of Ub to target proteins by Ub ligases, such as the Anaphase-Promoting Complex/Cyclosome (APC/C), is paramount for cell cycle transitions as it leads to the irreversible dest...

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Detalles Bibliográficos
Autores principales: Bodrug, Tatyana, Welsh, Kaeli A., Hinkle, Megan, Emanuele, Michael J., Brown, Nicholas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182066/
https://www.ncbi.nlm.nih.gov/pubmed/34109183
http://dx.doi.org/10.3389/fcell.2021.687515